atcc 6303 strain (ATCC)
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Atcc 6303 Strain, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 580 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 580 article reviews
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Article Title: Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection
Journal: bioRxiv
doi: 10.64898/2026.01.10.698720
Figure Legend Snippet: a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae ATCC-6303. Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .
Techniques Used: Infection, Virus, Two Tailed Test
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